Genetic Choreas

Ruth H. Walker; Dobrila Rudnicki; Russell L. Margolis

doi:10.1007/978-3-319-17223-1_8

Genetic Choreas

Ruth H. Walker
, Dobrila Rudnicki
, Russell L. Margolis

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The “genetic choreas” consist of a heterogeneous group of disorders, similar in that chorea is typically the most prominent or presenting clinical feature and that degeneration of the striatum is the most characteristic neuropathological feature. Here we discuss the prototypical hereditary choreiform disorder, Huntington’s disease (HD), and a series of other familial disorders in which chorea is more or less part of the clinical syndrome and that may resemble HD, including Huntington’s disease-like 2 (HDL2), the neuroacanthocytoses, benign hereditary chorea, the iron accumulation diseases, and paroxysmal movement disorders. We conclude by providing comprehensive tables of the dominant and nondominant genetic choreas.

Original language	English (US)
Title of host publication	Movement Disorder Genetics
Publisher	Springer International Publishing
Pages	147-167
Number of pages	21
ISBN (Electronic)	9783319172231
ISBN (Print)	9783319172224
DOIs	https://doi.org/10.1007/978-3-319-17223-1_8
State	Published - Jan 1 2015

Keywords

Basal ganglia
Chorea
Dyskinesia
Hereditary
Huntington’s disease
Neuroacanthocytosis

ASJC Scopus subject areas

General Medicine
General Biochemistry, Genetics and Molecular Biology
General Neuroscience

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10.1007/978-3-319-17223-1_8

Cite this

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KW - Huntington’s disease

KW - Neuroacanthocytosis

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Genetic Choreas

Abstract

Keywords

ASJC Scopus subject areas

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