TY - JOUR
T1 - Genetic characterization of an H2N2 influenza virus isolated from a muskrat in Western Siberia
AU - Gulyaeva, Marina
AU - Sharshov, Kirill
AU - Suzuki, Mizuho
AU - Sobolev, Ivan
AU - Sakoda, Yoshihiro
AU - Alekseev, Alexander
AU - Sivay, Mariya
AU - Shestopalova, Lidia
AU - Shchelkanov, Michael
AU - Shestopalov, Alexander
N1 - Funding Information:
ACKNOWLEDGMENTS. This study was supported by the Ministry of Education and Science of the Russian Federation (Project # RFMEFI61315X0045) and Russian Foundation for Basic Research (17-04-01919).
Publisher Copyright:
© 2017 The Japanese Society of Veterinary Science.
PY - 2017
Y1 - 2017
N2 - Thirty-two muskrats (Ondatra zibethicus) were captured for surveillance of avian influenza virus in wild waterfowl and mammals near Lake Chany, Western Siberia, Russia. A/muskrat/Russia/63/2014 (H2N2) was isolated from an apparently healthy muskrat using chicken embryos. Based on phylogenetic analysis, the hemagglutinin and neuraminidase genes of this isolate were classified into the Eurasian avian-like influenza virus clade and closely related to low pathogenic avian influenza viruses (LPAIVs) isolated from wild water birds in Italy and Sweden, respectively. Other internal genes were also closely related to LPAIVs isolated from Eurasian wild water birds. Results suggest that interspecies transmission of LPAIVs from wild water birds to semiaquatic mammals occurs, facilitating the spread and evolution of LPAIVs in wetland areas of Western Siberia.
AB - Thirty-two muskrats (Ondatra zibethicus) were captured for surveillance of avian influenza virus in wild waterfowl and mammals near Lake Chany, Western Siberia, Russia. A/muskrat/Russia/63/2014 (H2N2) was isolated from an apparently healthy muskrat using chicken embryos. Based on phylogenetic analysis, the hemagglutinin and neuraminidase genes of this isolate were classified into the Eurasian avian-like influenza virus clade and closely related to low pathogenic avian influenza viruses (LPAIVs) isolated from wild water birds in Italy and Sweden, respectively. Other internal genes were also closely related to LPAIVs isolated from Eurasian wild water birds. Results suggest that interspecies transmission of LPAIVs from wild water birds to semiaquatic mammals occurs, facilitating the spread and evolution of LPAIVs in wetland areas of Western Siberia.
KW - H2N2
KW - Influenza virus
KW - Muskrat
KW - Phylogenetic analysis
KW - Siberia
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U2 - 10.1292/jvms.17-0048
DO - 10.1292/jvms.17-0048
M3 - Article
C2 - 28690288
AN - SCOPUS:85027715040
SN - 0916-7250
VL - 79
SP - 1461
EP - 1465
JO - Journal of Veterinary Medical Science
JF - Journal of Veterinary Medical Science
IS - 8
ER -