Genetic augmentation of Ca2+ channels in cell monolayers: comparing optical recordings and computer simulations of modulated action potentials

Emilia Entcheva; Henry M. Colecraft; David Yue; Raimond Winslow; Leslie Tung

Genetic augmentation of Ca2+ channels in cell monolayers: comparing optical recordings and computer simulations of modulated action potentials

Emilia Entcheva, Henry M. Colecraft, David Yue, Raimond Winslow, Leslie Tung

School of Medicine

Research output: Contribution to journal › Conference article › peer-review

Abstract

Adenoviralmediated overexpression of β2a, 4 subunits was used to influence the electrophysiological behavior of confluent monolayers of cultured neonatal rat ventricular myocytes. Optical action potentials were recorded for control and a-subunit-enhanced monolayers. In general, overexpression of auxiliary β2a, a subunits significantly modulated excitability in hear monolayers.

Original language	English (US)
Pages (from-to)	S-53
Journal	Annals of biomedical engineering
Volume	28
Issue number	SUPPL. 1
State	Published - 2000
Event	2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000

ASJC Scopus subject areas

Biomedical Engineering

Cite this

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title = "Genetic augmentation of Ca2+ channels in cell monolayers: comparing optical recordings and computer simulations of modulated action potentials",

abstract = "Adenoviralmediated overexpression of β2a, 4 subunits was used to influence the electrophysiological behavior of confluent monolayers of cultured neonatal rat ventricular myocytes. Optical action potentials were recorded for control and a-subunit-enhanced monolayers. In general, overexpression of auxiliary β2a, a subunits significantly modulated excitability in hear monolayers.",

author = "Emilia Entcheva and Colecraft, {Henry M.} and David Yue and Raimond Winslow and Leslie Tung",

year = "2000",

language = "English (US)",

volume = "28",

pages = "S--53",

journal = "Annals of biomedical engineering",

issn = "0090-6964",

publisher = "Springer",

number = "SUPPL. 1",

note = "2000 Annual Fall Meeting of the Biomedical Engineering Society ; Conference date: 12-10-2000 Through 14-10-2000",

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TY - JOUR

T1 - Genetic augmentation of Ca2+ channels in cell monolayers

T2 - 2000 Annual Fall Meeting of the Biomedical Engineering Society

AU - Entcheva, Emilia

AU - Colecraft, Henry M.

AU - Yue, David

AU - Winslow, Raimond

AU - Tung, Leslie

PY - 2000

Y1 - 2000

N2 - Adenoviralmediated overexpression of β2a, 4 subunits was used to influence the electrophysiological behavior of confluent monolayers of cultured neonatal rat ventricular myocytes. Optical action potentials were recorded for control and a-subunit-enhanced monolayers. In general, overexpression of auxiliary β2a, a subunits significantly modulated excitability in hear monolayers.

AB - Adenoviralmediated overexpression of β2a, 4 subunits was used to influence the electrophysiological behavior of confluent monolayers of cultured neonatal rat ventricular myocytes. Optical action potentials were recorded for control and a-subunit-enhanced monolayers. In general, overexpression of auxiliary β2a, a subunits significantly modulated excitability in hear monolayers.

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UR - http://www.scopus.com/inward/citedby.url?scp=0034498571&partnerID=8YFLogxK

M3 - Conference article

AN - SCOPUS:0034498571

SN - 0090-6964

VL - 28

SP - S-53

JO - Annals of biomedical engineering

JF - Annals of biomedical engineering

IS - SUPPL. 1

Y2 - 12 October 2000 through 14 October 2000

ER -

Genetic augmentation of Ca2+ channels in cell monolayers: comparing optical recordings and computer simulations of modulated action potentials

Abstract

ASJC Scopus subject areas

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