Genetic and immunological mechanisms in the pathogenesis of systemic lupus erythematosus

Charles G. Drake; Brian L. Kotzin

doi:10.1016/0952-7915(92)90054-I

Genetic and immunological mechanisms in the pathogenesis of systemic lupus erythematosus

Charles G. Drake, Brian L. Kotzin

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Recent research in systemic lupus erythematosus and animal models of lupus has provided new insight into the pathogenesis of this complex autoimmune disease. Progress has been made towards understanding the genetic contributions to disease susceptibility and induction, as well as towards elucidation of the lymphocyte abnormalities involved in pathogenic autoantibody production.

Original language	English (US)
Pages (from-to)	733-740
Number of pages	8
Journal	Current Opinion in Immunology
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/0952-7915(92)90054-I
State	Published - 1992
Externally published	Yes

ASJC Scopus subject areas

Immunology
Immunology and Allergy

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title = "Genetic and immunological mechanisms in the pathogenesis of systemic lupus erythematosus",

abstract = "Recent research in systemic lupus erythematosus and animal models of lupus has provided new insight into the pathogenesis of this complex autoimmune disease. Progress has been made towards understanding the genetic contributions to disease susceptibility and induction, as well as towards elucidation of the lymphocyte abnormalities involved in pathogenic autoantibody production.",

author = "Drake, {Charles G.} and Kotzin, {Brian L.}",

year = "1992",

doi = "10.1016/0952-7915(92)90054-I",

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pages = "733--740",

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AU - Drake, Charles G.

AU - Kotzin, Brian L.

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AB - Recent research in systemic lupus erythematosus and animal models of lupus has provided new insight into the pathogenesis of this complex autoimmune disease. Progress has been made towards understanding the genetic contributions to disease susceptibility and induction, as well as towards elucidation of the lymphocyte abnormalities involved in pathogenic autoantibody production.

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JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

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Genetic and immunological mechanisms in the pathogenesis of systemic lupus erythematosus

Abstract

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