Abstract
Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by communication and social impairments, as well as repetitive behaviors. ASDs are highly heritable, but environmental contributions to risk are also likely. To date, only a few specific genes or environmental factors have been definitively characterized. Typically, genetic and environmental research in ASD etiology have been distinct pursuits, rather than carried out in a combined Gene-Environment context. This chapter offers evidence in support of both genetic and environmental etiology perspectives and suggestions for how to integrate the two fields moving forward, highlighting the potential benefits, and how to navigate particular challenges.
Original language | English (US) |
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Title of host publication | Frontiers in Autism Research: New Horizons for Diagnosis and Treatment |
Publisher | World Scientific Publishing Co. |
Pages | 335-374 |
Number of pages | 40 |
ISBN (Print) | 9789814602167, 9789814602150 |
DOIs | |
State | Published - Jan 1 2014 |
Keywords
- Environment
- Epigenetics
- Genetics
- Interaction
- Methylation
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)
- Neuroscience(all)