Genes and environment in autism spectrum disorders: An integrated perspective

Kelly M. Bakulski; Alison B. Singer; Daniele Daniele Fallin

doi:10.1142/9789814602167_0014

Genes and environment in autism spectrum disorders: An integrated perspective

Kelly M. Bakulski, Alison B. Singer, Daniele Daniele Fallin

Bloomberg School of Public Health

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by communication and social impairments, as well as repetitive behaviors. ASDs are highly heritable, but environmental contributions to risk are also likely. To date, only a few specific genes or environmental factors have been definitively characterized. Typically, genetic and environmental research in ASD etiology have been distinct pursuits, rather than carried out in a combined Gene-Environment context. This chapter offers evidence in support of both genetic and environmental etiology perspectives and suggestions for how to integrate the two fields moving forward, highlighting the potential benefits, and how to navigate particular challenges.

Original language	English (US)
Title of host publication	Frontiers in Autism Research: New Horizons for Diagnosis and Treatment
Publisher	World Scientific Publishing Co.
Pages	335-374
Number of pages	40
ISBN (Print)	9789814602167, 9789814602150
DOIs	https://doi.org/10.1142/9789814602167_0014
State	Published - Jan 1 2014

Keywords

Environment
Epigenetics
Genetics
Interaction
Methylation

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)
Neuroscience(all)

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10.1142/9789814602167_0014

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AB - Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by communication and social impairments, as well as repetitive behaviors. ASDs are highly heritable, but environmental contributions to risk are also likely. To date, only a few specific genes or environmental factors have been definitively characterized. Typically, genetic and environmental research in ASD etiology have been distinct pursuits, rather than carried out in a combined Gene-Environment context. This chapter offers evidence in support of both genetic and environmental etiology perspectives and suggestions for how to integrate the two fields moving forward, highlighting the potential benefits, and how to navigate particular challenges.

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KW - Genetics

KW - Interaction

KW - Methylation

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ER -

Genes and environment in autism spectrum disorders: An integrated perspective

Abstract

Keywords

ASJC Scopus subject areas

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