Genes and environment in autism spectrum disorders: An integrated perspective

Kelly M. Bakulski, Alison B. Singer, Daniele Daniele Fallin

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by communication and social impairments, as well as repetitive behaviors. ASDs are highly heritable, but environmental contributions to risk are also likely. To date, only a few specific genes or environmental factors have been definitively characterized. Typically, genetic and environmental research in ASD etiology have been distinct pursuits, rather than carried out in a combined Gene-Environment context. This chapter offers evidence in support of both genetic and environmental etiology perspectives and suggestions for how to integrate the two fields moving forward, highlighting the potential benefits, and how to navigate particular challenges.

Original languageEnglish (US)
Title of host publicationFrontiers in Autism Research: New Horizons for Diagnosis and Treatment
PublisherWorld Scientific Publishing Co.
Pages335-374
Number of pages40
ISBN (Print)9789814602167, 9789814602150
DOIs
StatePublished - Jan 1 2014

Keywords

  • Environment
  • Epigenetics
  • Genetics
  • Interaction
  • Methylation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)
  • Neuroscience(all)

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