Abstract
Amphotericin B, an anti-fungal polyene antibiotic, has profound immunomodulating properties in murine systems. Reports of similar effects in man are few. Amphotericin B 2.0 μg/ml reduced phytohemagglutinin-induced 3H-thymidine incorporation in peripheral blood mononuclear cells from control of 42,905 to 24,183 (experimental CPM minus control CPM) (p3 cells/well, AMB 87 ± 5 x 103 cells/well; p2 production during 18 hr of incubation from baseline 15.1 ± 2.8 ng/106 cells to 59.4 ± 17.8 ng/106 cells (p
Original language | English (US) |
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Pages (from-to) | 135-139 |
Number of pages | 5 |
Journal | Journal of Immunology |
Volume | 127 |
Issue number | 1 |
State | Published - 1981 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology