General methods for analysing repeated measures

Thomas A. Louis

Research output: Contribution to journalArticlepeer-review

70 Scopus citations


We present an overview of issues and methods for analysing repeated measures of a continuous random variable. We discuss modelling the mean vector and covariance structure, statistical efficiency, regression diagnostics, and discrepancies between longitudinal and cross‐sectional methods. We illustrate key points with examples and discuss areas requiring further development.

Original languageEnglish (US)
Pages (from-to)29-45
Number of pages17
JournalStatistics in Medicine
Issue number1-2
StatePublished - 1988
Externally publishedYes


  • Correlated errors
  • Dropout bias
  • Longitudinal data
  • Repeated measures

ASJC Scopus subject areas

  • Epidemiology
  • Statistics and Probability


Dive into the research topics of 'General methods for analysing repeated measures'. Together they form a unique fingerprint.

Cite this