TY - JOUR
T1 - Gender and survival after AIDS in Rio de Janeiro, Brazil
AU - Santoro-Lopes, Guilherme
AU - Harrison, Lee H.
AU - Moulton, Lawrence H.
AU - Lima, Luis Antonio Alves
AU - De Pinho, Ana Maria Felix
AU - Hofer, Cristina
AU - Schechter, Mauro
PY - 1998/12/1
Y1 - 1998/12/1
N2 - The relation between gender and survival after a diagnosis of AIDS was studied in a cohort of patients with HIV infection in Rio de Janeiro, Brazil. During the study period, 124 of 617 patients (20%) developed AIDS. Of this group, 91 patients were men and 33 were women. There were no gender related differences regarding the access to antiretroviral therapy or to prophylaxis for Pneumocystis carinii pneumonia. Survival was shorter among women (hazard ratio [HR] = 4.43; p < .001) after adjustment for age and AIDS-defining condition. Adjusting for CD4+ and CD8+ counts reduced the difference between genders (HR = 3.33; p = .017). These results suggest that survival after an AIDS diagnosis may be shorter among women than men in Brazil. Further studies are needed to determine the factors that may be negatively influencing the prognosis of women with AIDS in Brazil.
AB - The relation between gender and survival after a diagnosis of AIDS was studied in a cohort of patients with HIV infection in Rio de Janeiro, Brazil. During the study period, 124 of 617 patients (20%) developed AIDS. Of this group, 91 patients were men and 33 were women. There were no gender related differences regarding the access to antiretroviral therapy or to prophylaxis for Pneumocystis carinii pneumonia. Survival was shorter among women (hazard ratio [HR] = 4.43; p < .001) after adjustment for age and AIDS-defining condition. Adjusting for CD4+ and CD8+ counts reduced the difference between genders (HR = 3.33; p = .017). These results suggest that survival after an AIDS diagnosis may be shorter among women than men in Brazil. Further studies are needed to determine the factors that may be negatively influencing the prognosis of women with AIDS in Brazil.
KW - AIDS
KW - CD4 and CD8 lymphocyte counts
KW - Gender
KW - HIV
KW - Survival analysis
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U2 - 10.1097/00042560-199812010-00012
DO - 10.1097/00042560-199812010-00012
M3 - Article
C2 - 9833750
AN - SCOPUS:0032403529
SN - 1077-9450
VL - 19
SP - 403
EP - 407
JO - Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
JF - Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
IS - 4
ER -