Gastrointestinal and Hepatic Disease in Rheumatoid Arthritis

Ethan Craig; Laura C. Cappelli

doi:10.1016/j.rdc.2017.09.005

Gastrointestinal and Hepatic Disease in Rheumatoid Arthritis

Ethan Craig, Laura C. Cappelli

School of Medicine

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Gastrointestinal (GI) manifestations of rheumatoid arthritis (RA) are rare, but can be impactful for patients. Some GI processes are directly related to RA, whereas others may be sequelae of treatment or caused by concomitant autoimmune diseases. This article discusses the role of the GI tract in RA pathogenesis; the presentation, epidemiology, and diagnosis of RA-related GI manifestations; concomitant GI autoimmune diseases that may affect those with RA; and GI side effects of RA treatment. The importance of appropriately considering conditions unrelated to RA in the differential diagnosis when evaluating new GI symptoms in patients with RA is noted.

Original language	English (US)
Pages (from-to)	89-111
Number of pages	23
Journal	Rheumatic Disease Clinics of North America
Volume	44
Issue number	1
DOIs	https://doi.org/10.1016/j.rdc.2017.09.005
State	Published - Feb 2018

Keywords

Antirheumatic medications (DMARDs)
Gastrointestinal disease
Hepatic disease
Rheumatoid arthritis

ASJC Scopus subject areas

Rheumatology

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10.1016/j.rdc.2017.09.005

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title = "Gastrointestinal and Hepatic Disease in Rheumatoid Arthritis",

abstract = "Gastrointestinal (GI) manifestations of rheumatoid arthritis (RA) are rare, but can be impactful for patients. Some GI processes are directly related to RA, whereas others may be sequelae of treatment or caused by concomitant autoimmune diseases. This article discusses the role of the GI tract in RA pathogenesis; the presentation, epidemiology, and diagnosis of RA-related GI manifestations; concomitant GI autoimmune diseases that may affect those with RA; and GI side effects of RA treatment. The importance of appropriately considering conditions unrelated to RA in the differential diagnosis when evaluating new GI symptoms in patients with RA is noted.",

keywords = "Antirheumatic medications (DMARDs), Gastrointestinal disease, Hepatic disease, Rheumatoid arthritis",

author = "Ethan Craig and Cappelli, {Laura C.}",

note = "Funding Information: Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number T32AR048522 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

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AU - Cappelli, Laura C.

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N2 - Gastrointestinal (GI) manifestations of rheumatoid arthritis (RA) are rare, but can be impactful for patients. Some GI processes are directly related to RA, whereas others may be sequelae of treatment or caused by concomitant autoimmune diseases. This article discusses the role of the GI tract in RA pathogenesis; the presentation, epidemiology, and diagnosis of RA-related GI manifestations; concomitant GI autoimmune diseases that may affect those with RA; and GI side effects of RA treatment. The importance of appropriately considering conditions unrelated to RA in the differential diagnosis when evaluating new GI symptoms in patients with RA is noted.

AB - Gastrointestinal (GI) manifestations of rheumatoid arthritis (RA) are rare, but can be impactful for patients. Some GI processes are directly related to RA, whereas others may be sequelae of treatment or caused by concomitant autoimmune diseases. This article discusses the role of the GI tract in RA pathogenesis; the presentation, epidemiology, and diagnosis of RA-related GI manifestations; concomitant GI autoimmune diseases that may affect those with RA; and GI side effects of RA treatment. The importance of appropriately considering conditions unrelated to RA in the differential diagnosis when evaluating new GI symptoms in patients with RA is noted.

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KW - Hepatic disease

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Gastrointestinal and Hepatic Disease in Rheumatoid Arthritis

Abstract

Keywords

ASJC Scopus subject areas

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