Future research directions in asthma: An NHLBI working group report

Bruce D. Levy, Patricia J. Noel, Michelle M. Freemer, Michelle M. Cloutier, Steve N. Georas, Nizar N. Jarjour, Carole Ober, Prescott G. Woodruff, Kathleen C. Barnes, Bruce G. Bender, Carlos A. Camargo, Geoff L. Chupp, Loren C. Denlinger, John V. Fahy, Anne M. Fitzpatrick, Anne Fuhlbrigge, Ben M. Gaston, Tina V. Hartert, Jay K. Kolls, Susan V. LynchWendy C. Moore, Wayne J. Morgan, Kari C. Nadeau, Dennis R. Ownby, Julian Solway, Stanley J. Szefler, Sally E. Wenzel, Rosalind J. Wright, Robert A. Smith, Serpil C. Erzurum

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Asthma is a common chronic disease without cure. Our understanding of asthma onset, pathobiology, classification, and management has evolved substantially over the past decade; however, significant asthma-related morbidity and excess healthcare use and costs persist. To address this important clinical condition, the NHLBI convened a group of extramural investigators for an Asthma Research Strategic Planning workshop on September 18-19, 2014, to accelerate discoveries and their translation to patients. The workshop focused on (1) in utero and early-life origins of asthma, (2) the use of phenotypes and endotypes to classify disease, (3) defining disease modification, (4) disease management, and (5) implementation research. This report summarizes the workshop and produces recommendations to guide future research in asthma.

Original languageEnglish (US)
Pages (from-to)1366-1372
Number of pages7
JournalAmerican Journal of Respiratory and Critical Care Medicine
Issue number11
StatePublished - Dec 1 2015


  • Asthma
  • Disease modification
  • Implementation
  • Phenotype
  • Prevention

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


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