Fusion to Listeriolysin O and delivery by Listeria monocytogenes enhances the immunogenicity of HER-2/neu and reveals subdominant epitopes in the FVB/N mouse

Keyphrases

• Immunogenicity 100%
• Human Epidermal Growth Factor Receptor 2 (HER2) 100%
• Listeria Monocytogenes 100%
• Listeriolysin O 100%
• Subdominant Epitopes 100%
• Tumor 16%
• DNA Vaccine 16%
• Vaccine Construct 16%
• Overlapping Fragments 16%
• Breast Cancer 8%
• Epitope 8%
• Murine Model 8%
• Mammary Tumor 8%
• Recombinant 8%
• Transgenic Mice 8%
• CD8+ T Cells 8%
• Extracellular Domain 8%
• Fusion Protein 8%
• Antitumor Effect 8%
• Intracellular Domain 8%
• Non-haemolytic 8%
• CD8+ T Cell Epitopes 8%
• NT-2 8%
• CTL Response 8%
• In Vivo Depletion 8%
• 3T3 Cell Lines 8%
• Strain Control 8%

Immunology and Microbiology

• Epitope 100%
• Immunogenicity 100%
• FVB/N Mouse 100%
• Listeria monocytogenes 100%
• Vaccine Efficacy 75%
• Cytotoxic T-Cell 50%
• DNA Vaccine 50%
• Transgenic Mouse 25%
• 3T3 Cell Line 25%

Biochemistry, Genetics and Molecular Biology

• T Cell 100%
• CD8 100%
• Immunogenicity 100%
• FVB/N Mouse 100%
• Listeria monocytogenes 100%
• Transgenic Mouse 50%
• Fusion Protein 50%