Further analysis of psychotropic medication and severe problem behavior

John M. Falligant, Molly K. Bednar

Research output: Contribution to journalArticlepeer-review


Cox et al. (2021) recently outlined a number of analytic methods (i.e., procedures for estimating effect size, conditional rates, and nonparametric partial correlation tests) that may help quantify the relative contributions of psychotropic medication and behavioral interventions on problem behavior among individuals with intellectual and developmental disorders. The purpose of the current study was to examine the generality of these methods by applying these procedures in a novel clinical context (i.e., a hospital-based inpatient unit for severe problem behavior). We extended the procedures described by Cox to include a larger sample size, cases with more frequent, severe and treatment-resistant problem behavior, cases with both medication decreases and increases, and cases with at least one similar class of psychotropic medication in common (i.e., atypical antipsychotics). This work remains a proof of concept, but we replicated a number of the preliminary findings from Cox et al. Implications for future research and medication monitoring practices are discussed.

Original languageEnglish (US)
Pages (from-to)817-831
Number of pages15
JournalBehavioral Interventions
Issue number4
StatePublished - Nov 2021


  • medication
  • problem behavior
  • quantitative analysis of behavior

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Clinical Psychology
  • Psychiatry and Mental health


Dive into the research topics of 'Further analysis of psychotropic medication and severe problem behavior'. Together they form a unique fingerprint.

Cite this