TY - JOUR
T1 - Funding of US biomedical research, 2003-2008
AU - Dorsey, E. Ray
AU - De Roulet, Jason
AU - Thompson, Joel P.
AU - Reminick, Jason I.
AU - Thai, Ashley
AU - White-Stellato, Zachary
AU - Beck, Christopher A.
AU - George, Benjamin P.
AU - Moses, Hamilton
PY - 2010/1/13
Y1 - 2010/1/13
N2 - Context: With the exception of the American Recovery and Reinvestment Act, funding support for biomedical research in the United States has slowed after a decade of doubling. However, the extent and scope of slowing are largely unknown. Objective: To quantify funding of biomedical research in the United States from 2003 to 2008. Design: Publicly available data were used to quantify funding from government (federal, state, and local), private, and industry sources. Regression models were used to compare financial trends between 1994-2003 and 2003-2007. The numbers of new drug and device approvals by the US Food and Drug Administration over the same period were also evaluated. Main Outcome Measures: Funding and growth rates by source; numbers of US Food and Drug Administration approvals. Results: Biomedical research funding increased from $75.5 billion in 2003 to $101.1 billion in 2007. In 2008, funding from the National Institutes of Health and industry totaled $88.8 billion. In 2007, funding from these sources, adjusted for inflation, was $90.2 billion. Adjusted for inflation, funding from 2003 to 2007 increased by 14%, for a compound annual growth rate of 3.4%. By comparison, funding from 1994 to 2003 increased at an annual rate of 7.8% (P<.001). In 2007, industry (58%) was the largest funder, followed by the federal government (33%). Modest increase in funding was not accompanied by an increase in approvals for drugs or devices. In 2007, the United States spent an estimated 4.5% of its total health expenditures on biomedical research and 0.1% on health services research. Conclusion After a decade of doubling, the rate of increase in biomedical research funding slowed from 2003 to 2007, and after adjustment for inflation, the absolute level of funding from the National Institutes of Health and industry appears to have decreased by 2% in 2008.
AB - Context: With the exception of the American Recovery and Reinvestment Act, funding support for biomedical research in the United States has slowed after a decade of doubling. However, the extent and scope of slowing are largely unknown. Objective: To quantify funding of biomedical research in the United States from 2003 to 2008. Design: Publicly available data were used to quantify funding from government (federal, state, and local), private, and industry sources. Regression models were used to compare financial trends between 1994-2003 and 2003-2007. The numbers of new drug and device approvals by the US Food and Drug Administration over the same period were also evaluated. Main Outcome Measures: Funding and growth rates by source; numbers of US Food and Drug Administration approvals. Results: Biomedical research funding increased from $75.5 billion in 2003 to $101.1 billion in 2007. In 2008, funding from the National Institutes of Health and industry totaled $88.8 billion. In 2007, funding from these sources, adjusted for inflation, was $90.2 billion. Adjusted for inflation, funding from 2003 to 2007 increased by 14%, for a compound annual growth rate of 3.4%. By comparison, funding from 1994 to 2003 increased at an annual rate of 7.8% (P<.001). In 2007, industry (58%) was the largest funder, followed by the federal government (33%). Modest increase in funding was not accompanied by an increase in approvals for drugs or devices. In 2007, the United States spent an estimated 4.5% of its total health expenditures on biomedical research and 0.1% on health services research. Conclusion After a decade of doubling, the rate of increase in biomedical research funding slowed from 2003 to 2007, and after adjustment for inflation, the absolute level of funding from the National Institutes of Health and industry appears to have decreased by 2% in 2008.
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U2 - 10.1001/jama.2009.1987
DO - 10.1001/jama.2009.1987
M3 - Article
C2 - 20068207
AN - SCOPUS:73949089207
SN - 0098-7484
VL - 303
SP - 137
EP - 143
JO - JAMA
JF - JAMA
IS - 2
ER -