TY - JOUR
T1 - From puddles to planet
T2 - Modeling approaches to vector-borne diseases at varying resolution and scale
AU - Eckhoff, Philip A.
AU - Bever, Caitlin A.
AU - Gerardin, Jaline
AU - Wenger, Edward A.
AU - Smith, David L.
N1 - Funding Information:
PAE, CAB, JG, and EAW are funded by the Global Good Fund of Bellevue , WA and would like to acknowledge many helpful discussions with colleagues at the Institute for Disease Modeling and other collaborators. DLS acknowledges funding from the Bill & Melinda Gates Foundation [# OPP1110495 ] and support from the RAPIDD program of the Science & Technology Directorate, Department of Homeland Security, and the Fogarty International Center , National Institutes of Health ( http://www.fic.nih.gov ).
Publisher Copyright:
© 2015 The Authors. Published by Elsevier Inc.
PY - 2015/6/4
Y1 - 2015/6/4
N2 - Since the original Ross-Macdonald formulations of vector-borne disease transmission, there has been a broad proliferation of mathematical models of vector-borne disease, but many of these models retain most to all of the simplifying assumptions of the original formulations. Recently, there has been a new expansion of mathematical frameworks that contain explicit representations of the vector life cycle including aquatic stages, multiple vector species, host heterogeneity in biting rate, realistic vector feeding behavior, and spatial heterogeneity. In particular, there are now multiple frameworks for spatially explicit dynamics with movements of vector, host, or both. These frameworks are flexible and powerful, but require additional data to take advantage of these features. For a given question posed, utilizing a range of models with varying complexity and assumptions can provide a deeper understanding of the answers derived from models.
AB - Since the original Ross-Macdonald formulations of vector-borne disease transmission, there has been a broad proliferation of mathematical models of vector-borne disease, but many of these models retain most to all of the simplifying assumptions of the original formulations. Recently, there has been a new expansion of mathematical frameworks that contain explicit representations of the vector life cycle including aquatic stages, multiple vector species, host heterogeneity in biting rate, realistic vector feeding behavior, and spatial heterogeneity. In particular, there are now multiple frameworks for spatially explicit dynamics with movements of vector, host, or both. These frameworks are flexible and powerful, but require additional data to take advantage of these features. For a given question posed, utilizing a range of models with varying complexity and assumptions can provide a deeper understanding of the answers derived from models.
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U2 - 10.1016/j.cois.2015.05.002
DO - 10.1016/j.cois.2015.05.002
M3 - Review article
AN - SCOPUS:84934875565
SN - 2214-5745
VL - 10
SP - 118
EP - 123
JO - Current Opinion in Insect Science
JF - Current Opinion in Insect Science
ER -