TY - JOUR
T1 - From cosmos to connectomes
T2 - The evolution of data-intensive science
AU - Burns, Randal
AU - Vogelstein, Joshua T.
AU - Szalay, Alexander S.
N1 - Publisher Copyright:
© 2014 Elsevier Inc.
PY - 2014
Y1 - 2014
N2 - The analysis of data requires computation: originally by hand and more recently by computers. Different models of computing are designed and optimized for different kinds of data. In data-intensive science, the scale and complexity of data exceeds the comfort zone of local data stores on scientific workstations. Thus, cloud computing emerges as the preeminent model, utilizing data centers and high-performance clusters, enabling remote users to access and query subsets of the data efficiently. We examine how data-intensive computational systems originally built for cosmology, the Sloan Digital Sky Survey (SDSS), are now being used in connectomics, at the Open Connectome Project. We list lessons learned and outline the top challenges we expect to face. Success in computational connectomics would drastically reduce the time between idea and discovery, as SDSS did in cosmology.
AB - The analysis of data requires computation: originally by hand and more recently by computers. Different models of computing are designed and optimized for different kinds of data. In data-intensive science, the scale and complexity of data exceeds the comfort zone of local data stores on scientific workstations. Thus, cloud computing emerges as the preeminent model, utilizing data centers and high-performance clusters, enabling remote users to access and query subsets of the data efficiently. We examine how data-intensive computational systems originally built for cosmology, the Sloan Digital Sky Survey (SDSS), are now being used in connectomics, at the Open Connectome Project. We list lessons learned and outline the top challenges we expect to face. Success in computational connectomics would drastically reduce the time between idea and discovery, as SDSS did in cosmology.
UR - http://www.scopus.com/inward/record.url?scp=84922041937&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84922041937&partnerID=8YFLogxK
U2 - 10.1016/j.neuron.2014.08.045
DO - 10.1016/j.neuron.2014.08.045
M3 - Short survey
C2 - 25233306
AN - SCOPUS:84922041937
SN - 0896-6273
VL - 83
SP - 1249
EP - 1252
JO - Neuron
JF - Neuron
IS - 6
ER -