Frequency of sample submission for optimal utilization of the cell culture cytotoxicity assay for detection of Clostridium difficile toxin

Anita P. Borek; Deborah Z. Aird; Karen C. Carroll

doi:10.1128/JCM.43.6.2994-2995.2005

Frequency of sample submission for optimal utilization of the cell culture cytotoxicity assay for detection of Clostridium difficile toxin

Anita P. Borek, Deborah Z. Aird, Karen C. Carroll

School of Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

We reviewed the results of repeated sample submissions within a 7-day time frame for Clostridium difficile toxin testing. A total of 2,940 samples were tested during a 3-month period using a cell culture cytotoxicity assay (CCCA). The results from all second samples (n = 1,101) were concordant with the original test result. In only two cases (0.8%; n = 247) was a third sample positive when the first two samples were negative. In this study, submission of multiple samples for CCCA did not increase detection of Clostridium difficile infection.

Original language	English (US)
Pages (from-to)	2994-2995
Number of pages	2
Journal	Journal of clinical microbiology
Volume	43
Issue number	6
DOIs	https://doi.org/10.1128/JCM.43.6.2994-2995.2005
State	Published - Jun 2005

ASJC Scopus subject areas

Microbiology (medical)

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10.1128/JCM.43.6.2994-2995.2005

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Frequency of sample submission for optimal utilization of the cell culture cytotoxicity assay for detection of Clostridium difficile toxin

Abstract

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