Frailty in advanced heart failure: a systematic review

Sunita R. Jha, Hakeem S.K. Ha, Louise D. Hickman, Malin Hannu, Patricia M. Davidson, Peter S. Macdonald, Phillip J. Newton

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


Frailty is a common geriatric syndrome of increased vulnerability to adverse events. The prevalence of frailty among chronic heart failure (CHF) is high and confers a greater risk of adverse events including falls, hospitalisation and mortality. There have been few studies assessing frailty in CHF. A review of the key databases was conducted from 2004 to 2014 including the key search terms ‘frail elderly’ and ‘heart failure’. The following electronic databases were searched: Medline, Cumulative Index for Nursing and Allied Health and Academic Search Complete, with reference lists being manually searched. Articles were included if frailty was assessed using a valid measuring tool in a population with a confirmed diagnosis of CHF. The search yielded a total of 393 articles with 8 articles being selected for review. The prevalence of frailty among those with CHF was high, ranging from 18 to 54 %. The frailty phenotype and geriatric assessments tools were the most common frailty measures utilised; high rates of co-morbidity, hospitalisation and mortality were identified. Frailty is common in CHF and is associated with adverse outcomes.

Original languageEnglish (US)
Pages (from-to)553-560
Number of pages8
JournalHeart Failure Reviews
Issue number5
StatePublished - Sep 8 2015


  • Advanced heart failure
  • Frail elderly
  • Review

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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