Abstract
We examined the quinolone resistance-determining region (QRDR) of gyrA, gyrB, and parC of recently isolated fluoroquinolone-resistant S. dysenteriae type 1 strains from south Asia and compared data with fluoroquinolone- susceptible strains associated with previous epidemics of 1978, 1984, and 1994. In fluoroquinolone-resistant strains, double mutations (Ser83 → Leu, Asp87 → Asn or Gly) and a single mutation (Ser80 → Ile) were detected in the QRDRs of gyrA and parC, respectively.
Original language | English (US) |
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Pages (from-to) | 108-111 |
Number of pages | 4 |
Journal | Current Microbiology |
Volume | 52 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2006 |
Externally published | Yes |
ASJC Scopus subject areas
- Microbiology
- Applied Microbiology and Biotechnology