Fluconazole failure in the treatment of invasive mycoses

Thomas G. Evans, Jeanmarie Mayer, Samuel Cohen, David Classen, Karen Carroll

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Fluconazole is a recently licensed antifungal agent that has gained widespread use in the medical community. Despite a lack of controlled trials in invasive fungal infections, this agent is often prescribed because of ease of administration and concern over amphotericin B toxicity. Three cases of systemic fungal infections in which fluconazole use resulted in unambiguous microbiologic and clinical failure are reported.

Original languageEnglish (US)
Pages (from-to)1232-1235
Number of pages4
JournalJournal of Infectious Diseases
Issue number6
StatePublished - Dec 1991
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases


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