First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina

María A. Pando; Lindsay M. Eyzaguirre; Marcela Segura; Christian T. Bautista; Rubén Marone; Ana Ceballos; Silvia M. Montano; José L. Sánchez; Mercedes Weissenbacher; María M. Ávila; Jean K. Carr

doi:10.1186/1742-4690-3-59

First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina

María A. Pando
, Lindsay M. Eyzaguirre
, Marcela Segura
, Christian T. Bautista
, Rubén Marone
, Ana Ceballos
, Silvia M. Montano
, José L. Sánchez
, Mercedes Weissenbacher
, María M. Ávila
, Jean K. Carr

Research output: Contribution to journal › Article › peer-review

Abstract

We describe the genetic divesity of currently transmitted strains of HIV-1 in men who have sex with men (MSM) in Buenos Aires, Argentina between 2000 and 2004. Nearly full-length sequence analysis of 10 samples showed that 6 were subtype B, 3 were BF recombinant and I was a triple recombinant of subtypes B, C and F. The 3 BF recombinants were 3 different unique recombinant forms. Full genome analysis of one strain that was subtype F when sequenced in pol was found to be a triple recombinant. Gag and pol were predominantly subtype F, while gp 120 was subtype B; there were regions of subtype C interspersed throughout. The young man infected with this strain reported multiple sexual partners and sero-converted between May and November of 2004. This study reported for the first time the full genome analysis of a triple recombinant between subtypes B, C and F, that combines in one virus the three most common subtypes in South America.

Original language	English (US)
Article number	59
Journal	Retrovirology
Volume	3
DOIs	https://doi.org/10.1186/1742-4690-3-59
State	Published - Sep 7 2006
Externally published	Yes

ASJC Scopus subject areas

Virology
Infectious Diseases

Access to Document

10.1186/1742-4690-3-59

Cite this

@article{8e5f43640a164be691b25f6f577f6f44,

title = "First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina",

abstract = "We describe the genetic divesity of currently transmitted strains of HIV-1 in men who have sex with men (MSM) in Buenos Aires, Argentina between 2000 and 2004. Nearly full-length sequence analysis of 10 samples showed that 6 were subtype B, 3 were BF recombinant and I was a triple recombinant of subtypes B, C and F. The 3 BF recombinants were 3 different unique recombinant forms. Full genome analysis of one strain that was subtype F when sequenced in pol was found to be a triple recombinant. Gag and pol were predominantly subtype F, while gp 120 was subtype B; there were regions of subtype C interspersed throughout. The young man infected with this strain reported multiple sexual partners and sero-converted between May and November of 2004. This study reported for the first time the full genome analysis of a triple recombinant between subtypes B, C and F, that combines in one virus the three most common subtypes in South America.",

author = "Pando, \{Mar{\'i}a A.\} and Eyzaguirre, \{Lindsay M.\} and Marcela Segura and Bautista, \{Christian T.\} and Rub{\'e}n Marone and Ana Ceballos and Montano, \{Silvia M.\} and S{\'a}nchez, \{Jos{\'e} L.\} and Mercedes Weissenbacher and {\'A}vila, \{Mar{\'i}a M.\} and Carr, \{Jean K.\}",

year = "2006",

month = sep,

day = "7",

doi = "10.1186/1742-4690-3-59",

language = "English (US)",

volume = "3",

journal = "Retrovirology",

issn = "1742-4690",

publisher = "BioMed Central",

}

TY - JOUR

T1 - First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina

AU - Pando, María A.

AU - Eyzaguirre, Lindsay M.

AU - Segura, Marcela

AU - Bautista, Christian T.

AU - Marone, Rubén

AU - Ceballos, Ana

AU - Montano, Silvia M.

AU - Sánchez, José L.

AU - Weissenbacher, Mercedes

AU - Ávila, María M.

AU - Carr, Jean K.

PY - 2006/9/7

Y1 - 2006/9/7

N2 - We describe the genetic divesity of currently transmitted strains of HIV-1 in men who have sex with men (MSM) in Buenos Aires, Argentina between 2000 and 2004. Nearly full-length sequence analysis of 10 samples showed that 6 were subtype B, 3 were BF recombinant and I was a triple recombinant of subtypes B, C and F. The 3 BF recombinants were 3 different unique recombinant forms. Full genome analysis of one strain that was subtype F when sequenced in pol was found to be a triple recombinant. Gag and pol were predominantly subtype F, while gp 120 was subtype B; there were regions of subtype C interspersed throughout. The young man infected with this strain reported multiple sexual partners and sero-converted between May and November of 2004. This study reported for the first time the full genome analysis of a triple recombinant between subtypes B, C and F, that combines in one virus the three most common subtypes in South America.

AB - We describe the genetic divesity of currently transmitted strains of HIV-1 in men who have sex with men (MSM) in Buenos Aires, Argentina between 2000 and 2004. Nearly full-length sequence analysis of 10 samples showed that 6 were subtype B, 3 were BF recombinant and I was a triple recombinant of subtypes B, C and F. The 3 BF recombinants were 3 different unique recombinant forms. Full genome analysis of one strain that was subtype F when sequenced in pol was found to be a triple recombinant. Gag and pol were predominantly subtype F, while gp 120 was subtype B; there were regions of subtype C interspersed throughout. The young man infected with this strain reported multiple sexual partners and sero-converted between May and November of 2004. This study reported for the first time the full genome analysis of a triple recombinant between subtypes B, C and F, that combines in one virus the three most common subtypes in South America.

UR - https://www.scopus.com/pages/publications/33749163862

UR - https://www.scopus.com/pages/publications/33749163862#tab=citedBy

U2 - 10.1186/1742-4690-3-59

DO - 10.1186/1742-4690-3-59

M3 - Article

C2 - 16959032

AN - SCOPUS:33749163862

SN - 1742-4690

VL - 3

JO - Retrovirology

JF - Retrovirology

M1 - 59

ER -

First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this