Fine needle aspiration cytology of hepatic metastasis from a meningeal hemangiopericytoma: A case report

Hasan Ghaffar; Anil Parwani; Dorothy L. Rosenthal

doi:10.1159/000326517

Fine needle aspiration cytology of hepatic metastasis from a meningeal hemangiopericytoma: A case report

Hasan Ghaffar, Anil Parwani, Dorothy L. Rosenthal

School of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

BACKGROUND: Hemangiopericytomas (HPCs) are rare spindle cell tumors, constituting 2.5% of soft tissue neoplasms. Few reports have addressed the fine needle aspiration (FNA) cytology of HPC. CASE: We describe the FNA biopsy (FNAB) findings in a 44-year-old patient with a previously resected meningeal hemangiopericytoma. The patient underwent ultrasound-guided FNAB of a 16.0-cm, radiographically heterogeneous density in the liver. The FNA smear showed crowded, ovoid to spindle-shaped cells with poorly defined, scant cytoplasm. The neoplastic cells were positive for CD34 and negative for CD31, factor VIII, glial fibrillary acid protein and cytokeratin AE1/AE3, supporting a diagnosis of HPC and compatible with metastasis from the patient's cerebral tumor. CONCLUSION: This case documents the role of FNA cytology in confirming HPC.

Original language	English (US)
Pages (from-to)	281-286
Number of pages	6
Journal	Acta cytologica
Volume	47
Issue number	2
DOIs	https://doi.org/10.1159/000326517
State	Published - 2003

Keywords

Aspiration biopsy
Hemangiopericytoma
Liver cancer
Meningeal neoplasms
Metastasis

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

Access to Document

10.1159/000326517

Cite this

@article{4a61a836b286453aa931f87eacb907fa,

title = "Fine needle aspiration cytology of hepatic metastasis from a meningeal hemangiopericytoma: A case report",

abstract = "BACKGROUND: Hemangiopericytomas (HPCs) are rare spindle cell tumors, constituting 2.5% of soft tissue neoplasms. Few reports have addressed the fine needle aspiration (FNA) cytology of HPC. CASE: We describe the FNA biopsy (FNAB) findings in a 44-year-old patient with a previously resected meningeal hemangiopericytoma. The patient underwent ultrasound-guided FNAB of a 16.0-cm, radiographically heterogeneous density in the liver. The FNA smear showed crowded, ovoid to spindle-shaped cells with poorly defined, scant cytoplasm. The neoplastic cells were positive for CD34 and negative for CD31, factor VIII, glial fibrillary acid protein and cytokeratin AE1/AE3, supporting a diagnosis of HPC and compatible with metastasis from the patient's cerebral tumor. CONCLUSION: This case documents the role of FNA cytology in confirming HPC.",

keywords = "Aspiration biopsy, Hemangiopericytoma, Liver cancer, Meningeal neoplasms, Metastasis",

author = "Hasan Ghaffar and Anil Parwani and Rosenthal, {Dorothy L.}",

year = "2003",

doi = "10.1159/000326517",

language = "English (US)",

volume = "47",

pages = "281--286",

journal = "Acta cytologica",

issn = "0001-5547",

publisher = "Science Printers and Publishers Inc.",

number = "2",

}

TY - JOUR

T1 - Fine needle aspiration cytology of hepatic metastasis from a meningeal hemangiopericytoma

T2 - A case report

AU - Ghaffar, Hasan

AU - Parwani, Anil

AU - Rosenthal, Dorothy L.

PY - 2003

Y1 - 2003

N2 - BACKGROUND: Hemangiopericytomas (HPCs) are rare spindle cell tumors, constituting 2.5% of soft tissue neoplasms. Few reports have addressed the fine needle aspiration (FNA) cytology of HPC. CASE: We describe the FNA biopsy (FNAB) findings in a 44-year-old patient with a previously resected meningeal hemangiopericytoma. The patient underwent ultrasound-guided FNAB of a 16.0-cm, radiographically heterogeneous density in the liver. The FNA smear showed crowded, ovoid to spindle-shaped cells with poorly defined, scant cytoplasm. The neoplastic cells were positive for CD34 and negative for CD31, factor VIII, glial fibrillary acid protein and cytokeratin AE1/AE3, supporting a diagnosis of HPC and compatible with metastasis from the patient's cerebral tumor. CONCLUSION: This case documents the role of FNA cytology in confirming HPC.

AB - BACKGROUND: Hemangiopericytomas (HPCs) are rare spindle cell tumors, constituting 2.5% of soft tissue neoplasms. Few reports have addressed the fine needle aspiration (FNA) cytology of HPC. CASE: We describe the FNA biopsy (FNAB) findings in a 44-year-old patient with a previously resected meningeal hemangiopericytoma. The patient underwent ultrasound-guided FNAB of a 16.0-cm, radiographically heterogeneous density in the liver. The FNA smear showed crowded, ovoid to spindle-shaped cells with poorly defined, scant cytoplasm. The neoplastic cells were positive for CD34 and negative for CD31, factor VIII, glial fibrillary acid protein and cytokeratin AE1/AE3, supporting a diagnosis of HPC and compatible with metastasis from the patient's cerebral tumor. CONCLUSION: This case documents the role of FNA cytology in confirming HPC.

KW - Aspiration biopsy

KW - Hemangiopericytoma

KW - Liver cancer

KW - Meningeal neoplasms

KW - Metastasis

UR - http://www.scopus.com/inward/record.url?scp=0037346020&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037346020&partnerID=8YFLogxK

U2 - 10.1159/000326517

DO - 10.1159/000326517

M3 - Article

C2 - 12685202

AN - SCOPUS:0037346020

SN - 0001-5547

VL - 47

SP - 281

EP - 286

JO - Acta cytologica

JF - Acta cytologica

IS - 2

ER -

Fine needle aspiration cytology of hepatic metastasis from a meningeal hemangiopericytoma: A case report

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this