Fiber density index correlates with reduced fractional anisotropy in white matter of patients with glioblastoma

Tim P.L. Roberts; Fang Liu; Andrea Kassner; Susumu Mori; Abhijit Guha

Fiber density index correlates with reduced fractional anisotropy in white matter of patients with glioblastoma

Tim P.L. Roberts, Fang Liu, Andrea Kassner, Susumu Mori, Abhijit Guha

School of Medicine

Research output: Contribution to journal › Article › peer-review

98 Scopus citations

Abstract

A quantitative description of white matter fiber attenuation, the fiber density index (FDi) is described. This measure is derived from quantitative analysis of diffusion tensor imaging and reveals an index of the number of fiber paths traversing a region of interest. In this report, FDi is computed in 10 patients with glioblastoma multiforme, in white matter that is peritumoral and contralateral. FDi is shown to correlate significantly with fractional anisotropy.

Original language	English (US)
Pages (from-to)	2183-2186
Number of pages	4
Journal	American Journal of Neuroradiology
Volume	26
Issue number	9
State	Published - Dec 1 2005

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology

Cite this

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abstract = "A quantitative description of white matter fiber attenuation, the fiber density index (FDi) is described. This measure is derived from quantitative analysis of diffusion tensor imaging and reveals an index of the number of fiber paths traversing a region of interest. In this report, FDi is computed in 10 patients with glioblastoma multiforme, in white matter that is peritumoral and contralateral. FDi is shown to correlate significantly with fractional anisotropy.",

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AU - Roberts, Tim P.L.

AU - Liu, Fang

AU - Kassner, Andrea

AU - Mori, Susumu

AU - Guha, Abhijit

PY - 2005/12/1

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N2 - A quantitative description of white matter fiber attenuation, the fiber density index (FDi) is described. This measure is derived from quantitative analysis of diffusion tensor imaging and reveals an index of the number of fiber paths traversing a region of interest. In this report, FDi is computed in 10 patients with glioblastoma multiforme, in white matter that is peritumoral and contralateral. FDi is shown to correlate significantly with fractional anisotropy.

AB - A quantitative description of white matter fiber attenuation, the fiber density index (FDi) is described. This measure is derived from quantitative analysis of diffusion tensor imaging and reveals an index of the number of fiber paths traversing a region of interest. In this report, FDi is computed in 10 patients with glioblastoma multiforme, in white matter that is peritumoral and contralateral. FDi is shown to correlate significantly with fractional anisotropy.

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Fiber density index correlates with reduced fractional anisotropy in white matter of patients with glioblastoma

Abstract

ASJC Scopus subject areas

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