Abstract
This international, multicenter, prospective cohort study examines the outcome of pregnancies associated with aging gametes. Comparing pregnancies conceived at or near the peak mucus phase with those occurring before or after the peak provides a means of evaluating the effect of aging gametes. The outcome criteria are (1) rates of spontaneous abortion, (2) low birth weight, and (3) congenital malformations. Preliminary analysis shows a trend toward increased spontaneous abortion with aging gametes in certain subsets (women with prior pregnancy losses) but no effect on birth weight. Too few method failures have yet been studied to make a definitive statement on congenital malformations.
Original language | English (US) |
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Pages (from-to) | 1981-1982 |
Number of pages | 2 |
Journal | American journal of obstetrics and gynecology |
Volume | 165 |
Issue number | 6 |
DOIs | |
State | Published - 1991 |
Keywords
- Natural family planning
- aging gametes
- congenital malformations
- fetal outcome
- spontaneous abortion
ASJC Scopus subject areas
- Obstetrics and Gynecology