Favoring the risk-benefit balance for upper extremity transplantation--the Pittsburgh Protocol.

Vijay S. Gorantla, Gerald Brandacher, Stefan Schneeberger, Xin Xiao Zheng, Albert D. Donnenberg, Joseph E. Losee, W. P.Andrew Lee

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations


Upper extremity transplantation is an innovative reconstructive strategy with potential of immediate clinical application and the most near-term pay-off for select amputees, allowing reintegration into employment and society. Routine applicability and widespread impact of such strategies for the upper extremity amputees with devastating limb loss could be enabled by implementation of cellular therapies that integrate and unify the concepts of transplant tolerance induction with those of reconstructive transplantation. Such therapies offer the promise of minimizing the risks, maximizing the benefits and optimizing outcomes of these innovative procedures. Copyright Â

Original languageEnglish (US)
Pages (from-to)511-520, ix-x
JournalHand clinics
Issue number4
StatePublished - Nov 2011

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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