Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy

J. H. Biddison, D. H. Dembo, H. Spalt, M. G. Hayes, C. W. LeDoux

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A high incidence of mitral valve prolapse (MVP) has been reported in patients with X-linked Duchenne muscular dystrophy. In our study MVP was present in six of 22 Duchenne dystrophy cases (27%) followed in the Maryland General Hospital Muscular Dystrophy Clinic. In addition, seven carriers of Duchenne and X-linked benign (Becker) dystrophy had evidence of MVP. Autosomal dominant transmission of MVP was present in four families. The unusually high prevalence of MVP in families with X-linked muscular dystrophy may have potential value in the recognition of the carrier trait.

Original languageEnglish (US)
Pages (from-to)1299-1304
Number of pages6
JournalUnknown Journal
Issue number6
StatePublished - 1979
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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