Familial aggregation of panic disturbances in Parkinson's disease

Gregory M. Pontone, Justin Palanci, O. Joseph Bienvenu, Kung Yee Liang, Gerald Nestadt, Peter V. Rabins, James R. Williams, Laura Marsh

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Panic disorder has an elevated prevalence in Parkinson's disease (PD). To explore the basis for this co-occurrence, the familial aggregation of panic disorder was examined in patients with PD. Probands and relatives of patients with PD and panic disorder (PD-PANIC; N=20, N=115) and control probands with PD and no active psychiatric illness (PD-NA; N=17, N=108) were interviewed by phone, using a structured interview to determine panic status. Lifetime prevalence of panic and "panic-like" disorders was higher in PD-PANIC than in PD-NA relatives. Panic and "panic-like" disorders are familial disorders in PD.

Original languageEnglish (US)
Pages (from-to)417-424
Number of pages8
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number4
StatePublished - 2011

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


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