@inproceedings{e55b98af94f54e5f84b7071127f3a869,
title = "False dyssynchrony: Problem with image-based cardiac functional analysis using x-ray computed tomography",
abstract = "We have developed a digitally synthesized patient which we call {"}Zach{"} (Zero millisecond Adjustable Clinical Heart) phantom, which allows for an access to the ground truth and assessment of image-based cardiac functional analysis (CFA) using CT images with clinically realistic settings. The study using Zach phantom revealed a major problem with image-based CFA: {"}False dyssynchrony.{"} Even though the true motion of wall segments is in synchrony, it may appear to be dyssynchrony with the reconstructed cardiac CT images. It is attributed to how cardiac images are reconstructed and how wall locations are updated over cardiac phases. The presence and the degree of false dyssynchrony may vary from scan-to-scan, which could degrade the accuracy and the repeatability (or precision) of image-based CT-CFA exams.",
keywords = "Cardiac function analysis, Computed tomography, Dyssynchrony",
author = "Masafumi Kidoh and Zeyang Shen and Yuki Suzuki and Luisa Ciuffo and Hiroshi Ashikaga and Shiu-Kai Fung and Yoshito Otake and Zimmerman, {Stefan L.} and Lima, {Joao A.C.} and Takahiro Higuchi and Okkyun Lee and Yoshinobu Sato and Becker, {Lewis C.} and Fishman, {Elliot K.} and Katsuyuki Taguchi",
note = "Funding Information: This work was supported in part by NIH research grant No. R56 HL 125680 and Japan Government Grant MEXT/JSPS KAKENHI #26108004. Publisher Copyright: {\textcopyright} 2017 SPIE.; Medical Imaging 2017: Physics of Medical Imaging ; Conference date: 13-02-2017 Through 16-02-2017",
year = "2017",
doi = "10.1117/12.2250257",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Schmidt, {Taly Gilat} and Lo, {Joseph Y.} and Flohr, {Thomas G.}",
booktitle = "Medical Imaging 2017",
}