Failure of postictal growth hormone rise in a patient with thalamic lesions

Antonio Culebras; Myron Miller

doi:10.1212/wnl.35.6.904

Failure of postictal growth hormone rise in a patient with thalamic lesions

Antonio Culebras, Myron Miller

Research output: Contribution to journal › Article › peer-review

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Abstract

A patient with bilateral thalamic lesions had a spontaneous generalized convulsion during nocturnal polygraphic recording. Postictal measurements of cortisol and prolactin showed the expected rise of plasma values at 30 and 60 minutes after the seizure, but growth hormone did not increase. This observation suggests that suprahypothalamic mechanisms regulating growth hormone release differ from those involved in the neural control of cortisol-ACTH and prolactin secretion. The thalamus may intervene as a regulatory center in the release of growth hormone.

Original language	English (US)
Pages (from-to)	904-907
Number of pages	4
Journal	Neurology
Volume	35
Issue number	6
DOIs	https://doi.org/10.1212/wnl.35.6.904
State	Published - Jun 1985
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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abstract = "A patient with bilateral thalamic lesions had a spontaneous generalized convulsion during nocturnal polygraphic recording. Postictal measurements of cortisol and prolactin showed the expected rise of plasma values at 30 and 60 minutes after the seizure, but growth hormone did not increase. This observation suggests that suprahypothalamic mechanisms regulating growth hormone release differ from those involved in the neural control of cortisol-ACTH and prolactin secretion. The thalamus may intervene as a regulatory center in the release of growth hormone.",

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AB - A patient with bilateral thalamic lesions had a spontaneous generalized convulsion during nocturnal polygraphic recording. Postictal measurements of cortisol and prolactin showed the expected rise of plasma values at 30 and 60 minutes after the seizure, but growth hormone did not increase. This observation suggests that suprahypothalamic mechanisms regulating growth hormone release differ from those involved in the neural control of cortisol-ACTH and prolactin secretion. The thalamus may intervene as a regulatory center in the release of growth hormone.

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Failure of postictal growth hormone rise in a patient with thalamic lesions

Abstract

ASJC Scopus subject areas

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