Factors associated with pneumococcal polysaccharide vaccination of the elderly in Spain: A cross-sectional study

Angela Domínguez, Núria Soldevila, Diana Toledo, Pere Godoy, Núria Torner, Luis Force, Jesús Castilla, José María Mayoral, Sonia Tamames, Vicente Martín, Mikel Egurrola, Francisco Sanz, Jenaro Astray, PI12/02079 Working Group Project PI12/02079 Working Group, J. Díaz-Borrego, A. Morillo, M. J. Pérez-Lozano, J. Gutiérrez, M. Pérez-Ruiz, M. A. Fernández-SierraS. Rojo-Rello, R. Ortiz de Lejarazu, M. I. Fernández-Natal, T. Fernández-Villa, A. Pueyo, A. Vilella, A. Antón, G. Navarro, M. Riera, E. Espejo, M. D. Mas, R. Pérez, J. A. Cayla, C. Rius, I. Crespo, C. Izquierdo, R. Torra, M. F. Domínguez-Berjon, M. A. Gutiérrez, S. Jiménez, E. Gil, F. Martín, R. Génova-Maleras, M. C. Prados, F. Ezzine de Blas, J. C. Galan, E. Navas, L. Rodríguez, C. J. Álvarez, E. Banderas, J. Chamorro, I. Casado, J. Díaz, M. J. López de Goicoechea, M. Morales

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


ABSTRACT: Vaccination of the elderly is an important factor in limiting the impact of pneumonia in the community. The aim of this study was to investigate the factors associated with pneumococcal polysaccharide vaccination in patients aged ≥ 65 years hospitalized for causes unrelated to pneumonia, acute respiratory disease, or influenza-like illness in Spain. We made a cross-sectional study during 2013-2014. A bivariate analysis was performed comparing vaccinated and unvaccinated patients, taking into account sociodemographic variables and risk medical conditions. A multivariate analysis was performed using multilevel regression models. 921 patients were included; 403 (43.8%) had received the pneumococcal vaccine (394 received the polysaccharide vaccine). Visiting the general practitioner ≥ 3 times during the last year (OR = 1.79; 95% CI 1.25-2.57); having received the influenza vaccination in the 2013-14 season (OR = 2.57; 95% CI 1.72-3.84) or in any of the 3 previous seasons (OR = 11.70; 95% CI 7.42-18.45) were associated with receiving the pneumococcal polysaccharide vaccine. Pneumococcal vaccination coverage of hospitalized elderly people is low. The elderly need to be targeted about pneumococcal vaccination and activities that encourage healthcare workers to proactively propose vaccination might be useful. Educational campaigns aimed at the elderly could also help to increase vaccination coverages and reduce the burden of pneumococcal disease in the community.

Original languageEnglish (US)
Pages (from-to)1891-1899
Number of pages9
JournalHuman Vaccines and Immunotherapeutics
Issue number7
StatePublished - Jul 2 2016


  • elderly patients
  • immunization
  • pneumococcal vaccination
  • public health
  • vaccination

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pharmacology


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