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Fabrication of Drug Delivery Systems Using Self-Assembled Peptide Nanostructures

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Peptides offer several molecular attributes that enable their unique use for drug delivery. Their chemical design versatility, in combination with their ability to adopt specific secondary structures, provides a unique platform for the design of biomaterials with well-defined structural and biological features. Here we provide a brief review on the use of peptide-based self-assembling nanostructures as carriers to deliver small molecule hydrophobic drugs. We will first outline the rational design principles for constructing a drug delivery system, and then analyze several peptide-based systems that harness such designs.

Original languageEnglish (US)
Title of host publicationMicro and Nanofabrication Using Self-Assembled Biological Nanostructures
PublisherElsevier Inc.
Pages91-115
Number of pages25
ISBN (Electronic)9780323296526
ISBN (Print)9780323296427
DOIs
StatePublished - 2015
Externally publishedYes

Keywords

  • Anticancer drugs
  • Drug delivery
  • Peptides
  • Self-assembly
  • Supramolecular nanostructures

ASJC Scopus subject areas

  • General Engineering

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