Eyelid Dysfunction in Neurodegenerative, Neurogenetic, and Neurometabolic Disease

Ali G. Hamedani, Daniel R. Gold

Research output: Chapter in Book/Report/Conference proceedingChapter


Eyelid movement is neuroanatomically linked to eye movement, and thus eyelid abnormalities frequently accompany and sometimes precede or overshadow eye movement abnormalities in neurodegenerative disease. In this chapter, we summarize the various eyelid abnormalities that can occur in inherited and acquired neurodegenerative disorders in the context of the neuroanatomic pathways that are affected. The epidemiology and clinical approach to diagnosis and treatment of ptosis, eyelid retraction, abnormal spontaneous and reflexive blinking, blepharospasm, and eyelid apraxia will also be reviewed.

Original languageEnglish (US)
Title of host publicationContemporary Clinical Neuroscience
PublisherSpringer Nature
Number of pages26
StatePublished - 2019

Publication series

NameContemporary Clinical Neuroscience
ISSN (Print)2627-535X
ISSN (Electronic)2627-5341


  • Brainstem
  • Eyelid
  • Neuro-ophthalmology

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Neurology
  • Sensory Systems
  • Clinical Neurology


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