Extramedullary recurrence of acute lymphoblastic leukemia 15 years after initial diagnosis

Gary V. Burton, J. Brice Weinberg, Michael J. Borowitz

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


We describe a 19‐year‐old man with recurrence of a lymphoid malignancy involving the ethmoid sinus 15 years following diagnosis and 10 years after discontinuation of therapy for childhood acute lymphoblastic leukemia (ALL). The cytologic appearance and immunologic phenotype of the tumor cells suggest that this malignancy represents a recurrence of his original tumor. Initial relapse of ALL is unusual after 4 years of continuous remission off therapy. This case illustrates that late relapse can occur and may present with unusual sites of involvement.

Original languageEnglish (US)
Pages (from-to)255-257
Number of pages3
JournalMedical and Pediatric Oncology
Issue number4
StatePublished - 1984
Externally publishedYes


  • acute lymphoblastic leukemia
  • infancy and adulthood
  • late relapse
  • lymphoblastic lymphoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Cancer Research


Dive into the research topics of 'Extramedullary recurrence of acute lymphoblastic leukemia 15 years after initial diagnosis'. Together they form a unique fingerprint.

Cite this