Extracorporeal life support for a 5-week-old infant with idiopathic pulmonary hemosiderosis

Sherrill Gutierrez, Susanna Shaw, Shehlanoor Huseni, Shagun Sachdeva, John P. Costello, Sonali Basu, Dilip S. Nath, Darren Klugman

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Idiopathic pulmonary hemosiderosis is a rare disease defined by the triad of iron deficiency anemia, hemoptysis, and diffuse pulmonary infiltrates on chest radiograph. Idiopathic pulmonary hemosiderosis is known to cause dyspnea and, in some cases, acute onset of massive pulmonary hemorrhage which is traditionally treated with conventional mechanical ventilation or high-frequency oscillation in conjunction with immunosuppressive therapy. In this case report, we describe a 5-week-old infant presenting with hemoptysis, massive pulmonary hemorrhage, and significant hypercapnic respiratory failure. The patient failed conventional ventilation but responded well to extracorporeal life support that was initiated early in his course. Idiopathic pulmonary hemosiderosis was suspected in light of his response to high-dose steroids and was confirmed by subsequent lung biopsies. Conclusion: Patients with severe pulmonary hemorrhage secondary to idiopathic pulmonary hemosiderosis can be safely supported with extracorporeal life support when conventional therapies have been exhausted.

Original languageEnglish (US)
Pages (from-to)1573-1576
Number of pages4
JournalEuropean Journal of Pediatrics
Issue number12
StatePublished - Dec 2014
Externally publishedYes


  • ECMO
  • Extracorporeal life support
  • Extracorporeal membrane oxygenation
  • Idiopathic pulmonary hemosiderosis
  • Pediatric critical care
  • Pulmonary hemorrhage

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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