Extended-Infusion β-Lactam Therapy, Mortality, and Subsequent Antibiotic Resistance among Hospitalized Adults with Gram-Negative Bloodstream Infections

Keyphrases

• Lactams 100%
• Antibiotic Resistance 100%
• Hospitalized Adults 100%
• Gram-negative Bloodstream Infections 100%
• Extended Infusion 100%
• Propensity Score Matching 83%
• Adverse Events 50%
• Adjusted Odds Ratio 50%
• Resistance Emergence 50%
• Minimum Inhibitory Concentration 33%
• Severe Disease 33%
• Antibiotics 33%
• Matching Group 33%
• Seizure 16%
• United States 16%
• Clinical Outcomes 16%
• Fold Increase 16%
• Multivariable Regression 16%
• 4-fold 16%
• Statistical Analysis 16%
• Large Cohort 16%
• Patients Included 16%
• Intermediate Range 16%
• Reduced Mortality 16%
• Non-susceptible 16%
• Acute Kidney Injury 16%
• Survival Benefit 16%
• Stratified Analysis 16%
• Catheter-related Complications 16%
• Nearest Neighbor 16%
• State Hospital 16%
• Cytopenia 16%
• Potential Adverse Events 16%
• Intermittent Infusion 16%
• Matching without Replacement 16%
• Antibiotic Discontinuation 16%

Medicine and Dentistry

• Infusion 100%
• Antibiotic Resistance 100%
• Lactam 100%
• Bloodstream Infection 100%
• Propensity Score Matching 83%
• Adverse Event 66%
• Odds Ratio 50%
• Antibiotics 50%
• Disease 33%
• Cohort Analysis 33%
• Epileptic Seizure 16%
• Acute Kidney Injury 16%
• Catheter Complication 16%
• Cytopenia 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Lactam 100%
• Bloodstream Infection 100%
• Antibiotic Resistance 100%
• Adverse Event 66%
• Antibiotics 50%
• Disease 33%
• Cohort Study 33%
• Minimum Inhibitory Concentration 33%
• Acute Kidney Failure 16%
• Catheter Complication 16%
• Cytopenia 16%