Extended Coverage First-Pass Perfusion Imaging Using Slice-Interleaved TSENSE

Peter Kellman, J. A. Derbyshire, K. O. Agyeman, E. R. McVeigh, A. E. Arai

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Parallel imaging applied to first-pass, contrast-enhanced cardiac MR can yield greater spatial coverage for a fixed temporal resolution. The method combines rate R = 2 acceleration using TSENSE with shot-to-shot interleaving of two slices. The √R SNR loss is largely compensated for by a longer effective repetition time (TR) and increased flip angle associated with slice interleaving. In this manner, increased spatial coverage is achieved while comparable or better image quality is maintained. Single-heartbeat temporal resolution was accomplished with spatial coverage of eight slices at heart rates up to 71 bpm, six slices up to 95 bpm, and four slices up to 143 bpm. Experiments in normal subjects (N = 6) were performed to assess signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) values.

Original languageEnglish (US)
Pages (from-to)200-204
Number of pages5
JournalMagnetic Resonance in Medicine
Issue number1
StatePublished - Jan 2004
Externally publishedYes


  • Contrast agent
  • Heart
  • MRI
  • Perfusion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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