Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens

S. E. Valone; E. A. Rich; R. S. Wallis; J. J. Ellner

Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens

S. E. Valone, E. A. Rich, R. S. Wallis, J. J. Ellner

Research output: Contribution to journal › Article › peer-review

Abstract

Four mycobacterial preparations directly stimulated human blood monocytes and alveolar macrophages to produce tumor necrosis factor (TNF). Monoclonal antibody against TNF blocked (99%) TNF activity. Lipopolysaccharide was not responsible for the TNF activity generated; activity was unaffected in the presence of polymyxin B.

Original language	English (US)
Pages (from-to)	3313-3315
Number of pages	3
Journal	Infection and Immunity
Volume	56
Issue number	12
State	Published - 1988
Externally published	Yes

ASJC Scopus subject areas

Immunology

Cite this

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title = "Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens",

abstract = "Four mycobacterial preparations directly stimulated human blood monocytes and alveolar macrophages to produce tumor necrosis factor (TNF). Monoclonal antibody against TNF blocked (99%) TNF activity. Lipopolysaccharide was not responsible for the TNF activity generated; activity was unaffected in the presence of polymyxin B.",

author = "Valone, {S. E.} and Rich, {E. A.} and Wallis, {R. S.} and Ellner, {J. J.}",

year = "1988",

language = "English (US)",

volume = "56",

pages = "3313--3315",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "12",

}

TY - JOUR

T1 - Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens

AU - Valone, S. E.

AU - Rich, E. A.

AU - Wallis, R. S.

AU - Ellner, J. J.

PY - 1988

Y1 - 1988

N2 - Four mycobacterial preparations directly stimulated human blood monocytes and alveolar macrophages to produce tumor necrosis factor (TNF). Monoclonal antibody against TNF blocked (99%) TNF activity. Lipopolysaccharide was not responsible for the TNF activity generated; activity was unaffected in the presence of polymyxin B.

AB - Four mycobacterial preparations directly stimulated human blood monocytes and alveolar macrophages to produce tumor necrosis factor (TNF). Monoclonal antibody against TNF blocked (99%) TNF activity. Lipopolysaccharide was not responsible for the TNF activity generated; activity was unaffected in the presence of polymyxin B.

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M3 - Article

C2 - 3053456

AN - SCOPUS:0023806438

SN - 0019-9567

VL - 56

SP - 3313

EP - 3315

JO - Infection and Immunity

JF - Infection and Immunity

IS - 12

ER -

Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens

Abstract

ASJC Scopus subject areas

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