Expression of extraocular-superfast-myosin heavy chain in rat laryngeal muscles

Akihiro Shiotani, Paul W. Flint

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Superfast myosin heavy chain (MHC), which is found in jaw-closing muscle and extraocular muscle (EOM), may also be found in rat laryngeal muscles. Immunostaining and Western blot using anti-EOM antibody were performed to identify and localize EOM MHC in laryngeal muscles. Specific reactivity of laryngeal IIL MHC was confirmed by Western blot and on immunostaining, all fibers in the lateral part of thyroarytenoid muscle reacted with EOM antibody. A scattered pattern of positive fibers was observed in the medial part of the thyroarytenoid, the posterior cricoarytenoid and the lateral cricoarytenoid muscles. EOM MHC was not detected in the cricothyroid muscle. The expression of EOM MHC in rat laryngeal muscle is consistent with the functional demands of the airway protection reflex.

Original languageEnglish (US)
Pages (from-to)3639-3642
Number of pages4
Issue number16
StatePublished - Nov 16 1998


  • Extraocular muscle
  • Immunohistochemistry
  • Myosin heavy chain
  • Rat laryngeal muscle
  • Thyroarytenoid muscle
  • Western blot

ASJC Scopus subject areas

  • Neuroscience(all)


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