TY - GEN
T1 - Exploration of the optimal group-discriminating features using CC-ICA
AU - Sui, Jing
AU - Calhoun, Vince D.
PY - 2008
Y1 - 2008
N2 - A coefficient-constrained independent component analysis (CC-ICA) framework for second-level group analysis is proposed, which incorporates group membership information as a constraint into the mixing coefficients. Applications to simulated signals and hybrid fMRI data show that, compared with regular ICA, CC-ICA improves both the decomposition accuracy and the extraction sensitivity to group differences. CCICA is then applied to real fMRI data to explore the optimal tasks and features from 15 task combinations. Results are consistent with and extend various neuroimaging studies and may prove especially important for the identification of relevant biomarkers of brain disorders.
AB - A coefficient-constrained independent component analysis (CC-ICA) framework for second-level group analysis is proposed, which incorporates group membership information as a constraint into the mixing coefficients. Applications to simulated signals and hybrid fMRI data show that, compared with regular ICA, CC-ICA improves both the decomposition accuracy and the extraction sensitivity to group differences. CCICA is then applied to real fMRI data to explore the optimal tasks and features from 15 task combinations. Results are consistent with and extend various neuroimaging studies and may prove especially important for the identification of relevant biomarkers of brain disorders.
UR - http://www.scopus.com/inward/record.url?scp=70349690182&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349690182&partnerID=8YFLogxK
U2 - 10.1109/ACSSC.2008.5074651
DO - 10.1109/ACSSC.2008.5074651
M3 - Conference contribution
AN - SCOPUS:70349690182
SN - 9781424429417
T3 - Conference Record - Asilomar Conference on Signals, Systems and Computers
SP - 1410
EP - 1414
BT - 2008 42nd Asilomar Conference on Signals, Systems and Computers, ASILOMAR 2008
T2 - 2008 42nd Asilomar Conference on Signals, Systems and Computers, ASILOMAR 2008
Y2 - 26 October 2008 through 29 October 2008
ER -