Expired air carbon monoxide accumulation and elimination as a function of number of cigarettes smoked

Jack E. Henningfield; Maxine L. Stitzer; Roland R. Griffiths

doi:10.1016/0306-4603(80)90049-0

Expired air carbon monoxide accumulation and elimination as a function of number of cigarettes smoked

Jack E. Henningfield, Maxine L. Stitzer, Roland R. Griffiths

School of Medicine

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

Eight heavy cigarette smokers smoked varying numbers of cigarettes during sessions of approximately 8 hours in length. Expired air carbon monoxide (CO) levels were determined every 10 minutes during sessions using a portable breath analyzer. Under these conditions, orderly patterns of CO accumulation and elimination were revealed, both within and across subjects, although absolute rates of accumulation and elimination varied considerably across individuals. Peak CO values and the duration of elevation of CO level were directly related to number of cigarettes smoked. In general, the findings support the potential utility of this measure for smoking research and treatment.

Original language	English (US)
Pages (from-to)	265-272
Number of pages	8
Journal	Addictive Behaviors
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/0306-4603(80)90049-0
State	Published - 1980

ASJC Scopus subject areas

Medicine (miscellaneous)
Clinical Psychology
Toxicology
Psychiatry and Mental health

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10.1016/0306-4603(80)90049-0

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title = "Expired air carbon monoxide accumulation and elimination as a function of number of cigarettes smoked",

abstract = "Eight heavy cigarette smokers smoked varying numbers of cigarettes during sessions of approximately 8 hours in length. Expired air carbon monoxide (CO) levels were determined every 10 minutes during sessions using a portable breath analyzer. Under these conditions, orderly patterns of CO accumulation and elimination were revealed, both within and across subjects, although absolute rates of accumulation and elimination varied considerably across individuals. Peak CO values and the duration of elevation of CO level were directly related to number of cigarettes smoked. In general, the findings support the potential utility of this measure for smoking research and treatment.",

author = "Henningfield, {Jack E.} and Stitzer, {Maxine L.} and Griffiths, {Roland R.}",

note = "Funding Information: *This research was supported by USPHS Grant No. DA01935 and Baltimore City Hospitals Institutional Research Grant 507 RR-05556. We thank Drs. George E. Bigelow and Ira Liebson for their helpful comments on the manuscript, and Ms. Penny Edwards for her assistance in analyzing the data. Send reprint requests to Dr. Roland R. Griffiths, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.",

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T1 - Expired air carbon monoxide accumulation and elimination as a function of number of cigarettes smoked

AU - Henningfield, Jack E.

AU - Stitzer, Maxine L.

AU - Griffiths, Roland R.

N1 - Funding Information: *This research was supported by USPHS Grant No. DA01935 and Baltimore City Hospitals Institutional Research Grant 507 RR-05556. We thank Drs. George E. Bigelow and Ira Liebson for their helpful comments on the manuscript, and Ms. Penny Edwards for her assistance in analyzing the data. Send reprint requests to Dr. Roland R. Griffiths, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

PY - 1980

Y1 - 1980

N2 - Eight heavy cigarette smokers smoked varying numbers of cigarettes during sessions of approximately 8 hours in length. Expired air carbon monoxide (CO) levels were determined every 10 minutes during sessions using a portable breath analyzer. Under these conditions, orderly patterns of CO accumulation and elimination were revealed, both within and across subjects, although absolute rates of accumulation and elimination varied considerably across individuals. Peak CO values and the duration of elevation of CO level were directly related to number of cigarettes smoked. In general, the findings support the potential utility of this measure for smoking research and treatment.

AB - Eight heavy cigarette smokers smoked varying numbers of cigarettes during sessions of approximately 8 hours in length. Expired air carbon monoxide (CO) levels were determined every 10 minutes during sessions using a portable breath analyzer. Under these conditions, orderly patterns of CO accumulation and elimination were revealed, both within and across subjects, although absolute rates of accumulation and elimination varied considerably across individuals. Peak CO values and the duration of elevation of CO level were directly related to number of cigarettes smoked. In general, the findings support the potential utility of this measure for smoking research and treatment.

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Expired air carbon monoxide accumulation and elimination as a function of number of cigarettes smoked

Abstract

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