Experimental herpetic keratitis in the guinea pig

K. F. Tabbara, M. Okumoto, G. Smolin

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A model of herpetic keratitis with type I Herpesvirus hominis (HVH) was established in the guinea pig. Experimentally produced type I HVH infection in one eye evoked systemic immunity and produced significant protection against subsequent infections with type I HVH in both that eye and the fellow eye. The study emphasizes the species differences between the immune mechanisms of the guinea pig and the rabbit. The guinea pig appears to be better suited than the rabbit to the study of immunologic responses that control facultative intracellular corneal parasitism.

Original languageEnglish (US)
Pages (from-to)363-366
Number of pages4
JournalCanadian Journal of Ophthalmology
Issue number3
StatePublished - 1974
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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