Experimental determination of enhancement factors from supercritical-fluid chromatography

B. O. Brown, A. J. Kishbaugh, M. E. Paulaitis

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


An experimental technique is described which involves the application of SCF chromatography to predicting enhancement factors in supercritical fluids at elevated pressures. We consider an important step in the development of this application: the determination of solute fugacities in the stationary phase of the chromatograph column. Experimental results are presented for chromatographic retention times of several aromatic hydrocarbons in a column with supercritical CO2 as the carrier fluid and a stationary phase of octadecylsilica particles. The measurements are used to determine the mechanism of solute retention in the column, and to develop a thermodyanmic correlation for predicting solute fugacities in the stationary phase.

Original languageEnglish (US)
Pages (from-to)247-261
Number of pages15
JournalFluid Phase Equilibria
Issue numberC
StatePublished - Oct 2 1987
Externally publishedYes

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry


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