Expeditious synthesis of hippuristanol and congeners with potent antiproliferative activities

Wei Li; Yongjun Dang; Jun O. Liu; Biao Yu

doi:10.1002/chem.200901732

Expeditious synthesis of hippuristanol and congeners with potent antiproliferative activities

Wei Li, Yongjun Dang, Jun O. Liu, Biao Yu

School of Medicine

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Rapid access : An expeditious synthesis of hippuristanol was developed that allowed rapid access to a number of analogues with structural alteration at its E and F rings (see scheme), facilitating the structure-activity relationship studies of the novel inhibitor of eukaryotic translation initiation.

Original language	English (US)
Pages (from-to)	10356-10359
Number of pages	4
Journal	Chemistry - A European Journal
Volume	15
Issue number	40
DOIs	https://doi.org/10.1002/chem.200901732
State	Published - Oct 12 2009

Keywords

Cancer
Natural products
Steroids
Structureactivity relationships

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1002/chem.200901732

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title = "Expeditious synthesis of hippuristanol and congeners with potent antiproliferative activities",

abstract = "Rapid access : An expeditious synthesis of hippuristanol was developed that allowed rapid access to a number of analogues with structural alteration at its E and F rings (see scheme), facilitating the structure-activity relationship studies of the novel inhibitor of eukaryotic translation initiation.",

keywords = "Cancer, Natural products, Steroids, Structureactivity relationships",

author = "Wei Li and Yongjun Dang and Liu, {Jun O.} and Biao Yu",

year = "2009",

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doi = "10.1002/chem.200901732",

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AU - Li, Wei

AU - Dang, Yongjun

AU - Liu, Jun O.

AU - Yu, Biao

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Y1 - 2009/10/12

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KW - Cancer

KW - Natural products

KW - Steroids

KW - Structureactivity relationships

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M3 - Article

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Expeditious synthesis of hippuristanol and congeners with potent antiproliferative activities

Abstract

Keywords

ASJC Scopus subject areas

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