Excimer laser photorefractive keratectomy

Theo Seiler, Peter J. McDonnell

Research output: Contribution to journalReview articlepeer-review

248 Scopus citations


Excimer laser photorefractive keratectomy has been used for the correction of myopia, hyperopia and astigmatism. This laser removes tissue through a process termed photoablative decomposition, in which incident photon energy is sufficient to break molecular bonds. Selective removal of tissue across the anterior corneal surface results in a change in anterior corneal curvature. The surgical outcome may be influenced also by interindividual variability in wound healing and pharmacologic interventions. The nature of the excimer laser-tissue interaction, and clinical outcomes of predictability, stability and complications of surgery for myopia are discussed in detail.

Original languageEnglish (US)
Pages (from-to)89-118
Number of pages30
JournalSurvey of ophthalmology
Issue number2
StatePublished - 1995
Externally publishedYes


  • excimer laser
  • myopia
  • photoablation
  • photorefractive keratectomy
  • refractive surgery

ASJC Scopus subject areas

  • Ophthalmology


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