Examining the association between MAOA genotype and incarceration, anger and hostility: The moderating influences of risk and protective factors

Kevin M. Beaver; Joseph L. Nedelec; Meghan Wilde; Courtney Lippoff; Dylan Jackson

doi:10.1016/j.jrp.2011.02.007

Examining the association between MAOA genotype and incarceration, anger and hostility: The moderating influences of risk and protective factors

Kevin M. Beaver, Joseph L. Nedelec, Meghan Wilde, Courtney Lippoff, Dylan Jackson

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Findings from molecular genetic research have indicated that a polymorphism in the promoter region of the MAOA gene interacts with environmental liabilities to predict antisocial phenotypes. We use these findings as a springboard to examine whether a global protective-risk factor index moderates the effect of MAOA genotype on the probability of being incarcerated and on a measure of anger and hostility. Analysis of data from the National Longitudinal Study of Adolescent Health (Add Health) indicates that exposure to risk and protective factors in adolescence are able to moderate the effect of MAOA genotype on anger and hostility in adulthood for males. The results in relation to the probability of being incarcerated were consistently null.

Original language	English (US)
Pages (from-to)	279-284
Number of pages	6
Journal	Journal of Research in Personality
Volume	45
Issue number	3
DOIs	https://doi.org/10.1016/j.jrp.2011.02.007
State	Published - Jun 2011
Externally published	Yes

Keywords

Add Health
Anger
Gene-environment interaction
Hostility
Incarceration
MAOA

ASJC Scopus subject areas

Social Psychology
Psychology(all)

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10.1016/j.jrp.2011.02.007

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title = "Examining the association between MAOA genotype and incarceration, anger and hostility: The moderating influences of risk and protective factors",

abstract = "Findings from molecular genetic research have indicated that a polymorphism in the promoter region of the MAOA gene interacts with environmental liabilities to predict antisocial phenotypes. We use these findings as a springboard to examine whether a global protective-risk factor index moderates the effect of MAOA genotype on the probability of being incarcerated and on a measure of anger and hostility. Analysis of data from the National Longitudinal Study of Adolescent Health (Add Health) indicates that exposure to risk and protective factors in adolescence are able to moderate the effect of MAOA genotype on anger and hostility in adulthood for males. The results in relation to the probability of being incarcerated were consistently null.",

keywords = "Add Health, Anger, Gene-environment interaction, Hostility, Incarceration, MAOA",

author = "Beaver, {Kevin M.} and Nedelec, {Joseph L.} and Meghan Wilde and Courtney Lippoff and Dylan Jackson",

note = "Funding Information: This research uses data from Add Health, a program project directed by Kathleen Mullan Harris and designed by J. Richard Udry, Peter S. Bearman, and Kathleen Mullan Harris at the University of North Carolina at Chapel Hill, and funded by grant P01-HD31921 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, with cooperative funding from 23 other federal agencies and foundations. Special acknowledgment is due Ronald R. Rindfuss and Barbara Entwisle for assistance in the original design. Information on how to obtain the Add Health data files is available on the Add Health website ( http://www.cpc.unc.edu/addhealth ). No direct support was received from grant P01-HD31921 for this analysis.",

year = "2011",

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doi = "10.1016/j.jrp.2011.02.007",

language = "English (US)",

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AU - Nedelec, Joseph L.

AU - Wilde, Meghan

AU - Lippoff, Courtney

AU - Jackson, Dylan

N1 - Funding Information: This research uses data from Add Health, a program project directed by Kathleen Mullan Harris and designed by J. Richard Udry, Peter S. Bearman, and Kathleen Mullan Harris at the University of North Carolina at Chapel Hill, and funded by grant P01-HD31921 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, with cooperative funding from 23 other federal agencies and foundations. Special acknowledgment is due Ronald R. Rindfuss and Barbara Entwisle for assistance in the original design. Information on how to obtain the Add Health data files is available on the Add Health website ( http://www.cpc.unc.edu/addhealth ). No direct support was received from grant P01-HD31921 for this analysis.

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N2 - Findings from molecular genetic research have indicated that a polymorphism in the promoter region of the MAOA gene interacts with environmental liabilities to predict antisocial phenotypes. We use these findings as a springboard to examine whether a global protective-risk factor index moderates the effect of MAOA genotype on the probability of being incarcerated and on a measure of anger and hostility. Analysis of data from the National Longitudinal Study of Adolescent Health (Add Health) indicates that exposure to risk and protective factors in adolescence are able to moderate the effect of MAOA genotype on anger and hostility in adulthood for males. The results in relation to the probability of being incarcerated were consistently null.

AB - Findings from molecular genetic research have indicated that a polymorphism in the promoter region of the MAOA gene interacts with environmental liabilities to predict antisocial phenotypes. We use these findings as a springboard to examine whether a global protective-risk factor index moderates the effect of MAOA genotype on the probability of being incarcerated and on a measure of anger and hostility. Analysis of data from the National Longitudinal Study of Adolescent Health (Add Health) indicates that exposure to risk and protective factors in adolescence are able to moderate the effect of MAOA genotype on anger and hostility in adulthood for males. The results in relation to the probability of being incarcerated were consistently null.

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KW - Gene-environment interaction

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KW - Incarceration

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Examining the association between MAOA genotype and incarceration, anger and hostility: The moderating influences of risk and protective factors

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Keywords

ASJC Scopus subject areas

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