Evolving risk factors for infectious complications of cancer therapy

S. Chanock

Research output: Contribution to journalReview articlepeer-review

72 Scopus citations


Advances in the supportive care of cancer patients have led to improved long-term outcomes. Infection, however, remains the most significant complication of cancer therapy. The author reviews the impact of new cancer therapies on the risk factors for infectious complications and the impact of therapy on the alterations in host defense. The relative importance of therapy-induced changes are contrasted with immunologic abnormalities associated with specific cancers. In addition, the author contrasts these changes with the infectious complications of human immunodeficiency virus infection, highlighting common themes in immunocompromised patients.

Original languageEnglish (US)
Pages (from-to)771-793
Number of pages23
JournalHematology/Oncology Clinics of North America
Issue number4
StatePublished - 1993

ASJC Scopus subject areas

  • Hematology
  • Oncology


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