TY - JOUR
T1 - Evolution of Neovascularization in Sickle Cell Retinopathy
T2 - A Prospective Fluorescein Angiographic Study
AU - Raichand, Motilal
AU - Goldberg, Morton F.
AU - Nagpal, Krishan C.
AU - Goldbaum, Michael H.
AU - Asdourian, George K.
PY - 1977/9
Y1 - 1977/9
N2 - With prospective observations we have documented by fluorescein angiography the development of retinal neovascularization in the eyes of patients with sickle cell-hemoglobin C disease (hemoglobin SC). In each patient, arteriolarvenular (AV) anastomoses occurred before the development of neovascular sea fans. To our knowledge, this report constitutes the first such documentation in the literature. New sea fans from AV anastomoses appeared throughout an average interval of 18 months (range, 8 to 36 months) in approximately 21% of young adutls with hemoglobin SC. Each year approximately 14% of young patients with hemoglobin SC may develop retinal neovascularization.
AB - With prospective observations we have documented by fluorescein angiography the development of retinal neovascularization in the eyes of patients with sickle cell-hemoglobin C disease (hemoglobin SC). In each patient, arteriolarvenular (AV) anastomoses occurred before the development of neovascular sea fans. To our knowledge, this report constitutes the first such documentation in the literature. New sea fans from AV anastomoses appeared throughout an average interval of 18 months (range, 8 to 36 months) in approximately 21% of young adutls with hemoglobin SC. Each year approximately 14% of young patients with hemoglobin SC may develop retinal neovascularization.
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U2 - 10.1001/archopht.1977.04450090065005
DO - 10.1001/archopht.1977.04450090065005
M3 - Article
C2 - 561589
AN - SCOPUS:0017662732
SN - 0003-9950
VL - 95
SP - 1543
EP - 1552
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 9
ER -