Evidence for two distinct classes of unmyelinated nociceptive afferents in monkey

Richard A. Meyer; James N. Campbell

doi:10.1016/0006-8993(81)91124-0

Evidence for two distinct classes of unmyelinated nociceptive afferents in monkey

Richard A. Meyer, James N. Campbell

School of Medicine

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Unmyelinated nociceptive afferents, responsive to intense mechanical and heat stimuli, exhibited either a quickly adapting or slowly adapting response to step increases in skin temperature. These two classes of C fibers were found to differ also in other properties. The quickly adapting C fibers had significantly lower thresholds to mechanical and heat stimuli, and smaller receptive field areas than the slowly adapting C fibers.

Original language	English (US)
Pages (from-to)	149-152
Number of pages	4
Journal	Brain research
Volume	224
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(81)91124-0
State	Published - Nov 9 1981

Keywords

cutaneous sensation
itch
nociceptor
pain
peripheral nerve
somatosensory system
thermal sensation
unmyelinated afferents

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(81)91124-0

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abstract = "Unmyelinated nociceptive afferents, responsive to intense mechanical and heat stimuli, exhibited either a quickly adapting or slowly adapting response to step increases in skin temperature. These two classes of C fibers were found to differ also in other properties. The quickly adapting C fibers had significantly lower thresholds to mechanical and heat stimuli, and smaller receptive field areas than the slowly adapting C fibers.",

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AU - Campbell, James N.

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AB - Unmyelinated nociceptive afferents, responsive to intense mechanical and heat stimuli, exhibited either a quickly adapting or slowly adapting response to step increases in skin temperature. These two classes of C fibers were found to differ also in other properties. The quickly adapting C fibers had significantly lower thresholds to mechanical and heat stimuli, and smaller receptive field areas than the slowly adapting C fibers.

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KW - nociceptor

KW - pain

KW - peripheral nerve

KW - somatosensory system

KW - thermal sensation

KW - unmyelinated afferents

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Evidence for two distinct classes of unmyelinated nociceptive afferents in monkey

Abstract

Keywords

ASJC Scopus subject areas

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