Evidence for linkage to chromosome 13q32 in an independent sample of schizophrenia families

J. G. Mulle; J. A. McDonough; K. V. Chowdari; V. Nimgaonkar; A. Chakravarti

doi:10.1038/sj.mp.4001639

Evidence for linkage to chromosome 13q32 in an independent sample of schizophrenia families

J. G. Mulle, J. A. McDonough, K. V. Chowdari, V. Nimgaonkar, A. Chakravarti

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Linkage analysis has identified chromosome 13q32 as a putative susceptibility locus for schizophrenia, although this region has not been replicated in all studies. The authors focused on this region, and investigated evidence for linkage in a sample of sib-pair pedigrees affected with schizophrenia. Nonparametric analysis revealed significant evidence for linkage at this region. This finding is consistent with previous reports of linkage, and enhances the plausibility of chromosome 13q32 as a true schizophrenia susceptibility locus.

Original language	English (US)
Pages (from-to)	429-431+423
Journal	Molecular psychiatry
Volume	10
Issue number	5
DOIs	https://doi.org/10.1038/sj.mp.4001639
State	Published - May 2005
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Psychiatry and Mental health
Cellular and Molecular Neuroscience

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abstract = "Linkage analysis has identified chromosome 13q32 as a putative susceptibility locus for schizophrenia, although this region has not been replicated in all studies. The authors focused on this region, and investigated evidence for linkage in a sample of sib-pair pedigrees affected with schizophrenia. Nonparametric analysis revealed significant evidence for linkage at this region. This finding is consistent with previous reports of linkage, and enhances the plausibility of chromosome 13q32 as a true schizophrenia susceptibility locus.",

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AU - Chowdari, K. V.

AU - Nimgaonkar, V.

AU - Chakravarti, A.

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AB - Linkage analysis has identified chromosome 13q32 as a putative susceptibility locus for schizophrenia, although this region has not been replicated in all studies. The authors focused on this region, and investigated evidence for linkage in a sample of sib-pair pedigrees affected with schizophrenia. Nonparametric analysis revealed significant evidence for linkage at this region. This finding is consistent with previous reports of linkage, and enhances the plausibility of chromosome 13q32 as a true schizophrenia susceptibility locus.

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Evidence for linkage to chromosome 13q32 in an independent sample of schizophrenia families

Abstract

ASJC Scopus subject areas

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