Evidence for an HPV one-dose schedule

Margaret Stanley, Anne Schuind, Kirthini K. Muralidharan, Dominique Guillaume, Victoria Willens, Hannah Borda, Marley Jurgensmeyer, Rupali Limaye

Research output: Contribution to journalArticlepeer-review

Abstract

The World Health Organization has recently updated their dosing schedule recommendations for the human papillomavirus (HPV) vaccine to include a single-dose schedule. We review the biologic plausibility of a single dose, the evidence from clinical trials, post-licensure observational studies, and mathematical modeling for a single-dose schedule. We also discuss the implications of countries switching to a single-dose program from a two or three-dose schedule. Finally, we review the countries that have currently switched to or introduced the vaccine with a single-dose schedule.

Original languageEnglish (US)
Pages (from-to)S16-S21
JournalVaccine
Volume42
DOIs
StatePublished - Jul 11 2024

Keywords

  • Dosing Schedule
  • HPV Vaccine
  • Immunisation Programmes

ASJC Scopus subject areas

  • Molecular Medicine
  • General Immunology and Microbiology
  • General Veterinary
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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