Even Cancers Want Commitment: Lineage Identity and Medulloblastoma Formation

Charles G. Eberhart

doi:10.1016/j.ccr.2008.07.011

Even Cancers Want Commitment: Lineage Identity and Medulloblastoma Formation

Charles G. Eberhart

School of Medicine

Research output: Contribution to journal › Short survey › peer-review

21 Scopus citations

Abstract

In this issue of Cancer Cell, Yang et al. (2008) and Schüller et al. (2008) show that Hedgehog activation in either multipotent neural stem cells or developmentally restricted progenitors causes only medulloblastomas to form. These data suggest that some stem cell-derived tumors must commit to a specific lineage in order to grow.

Original language	English (US)
Pages (from-to)	105-107
Number of pages	3
Journal	Cancer cell
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/j.ccr.2008.07.011
State	Published - Aug 12 2008

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2008.07.011

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@article{3dc62ea7e45c47f5a1384089be98bdbd,

title = "Even Cancers Want Commitment: Lineage Identity and Medulloblastoma Formation",

abstract = "In this issue of Cancer Cell, Yang et al. (2008) and Sch{\"u}ller et al. (2008) show that Hedgehog activation in either multipotent neural stem cells or developmentally restricted progenitors causes only medulloblastomas to form. These data suggest that some stem cell-derived tumors must commit to a specific lineage in order to grow.",

author = "Eberhart, {Charles G.}",

year = "2008",

month = aug,

day = "12",

doi = "10.1016/j.ccr.2008.07.011",

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journal = "Cancer cell",

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publisher = "Cell Press",

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T1 - Even Cancers Want Commitment

T2 - Lineage Identity and Medulloblastoma Formation

AU - Eberhart, Charles G.

PY - 2008/8/12

Y1 - 2008/8/12

N2 - In this issue of Cancer Cell, Yang et al. (2008) and Schüller et al. (2008) show that Hedgehog activation in either multipotent neural stem cells or developmentally restricted progenitors causes only medulloblastomas to form. These data suggest that some stem cell-derived tumors must commit to a specific lineage in order to grow.

AB - In this issue of Cancer Cell, Yang et al. (2008) and Schüller et al. (2008) show that Hedgehog activation in either multipotent neural stem cells or developmentally restricted progenitors causes only medulloblastomas to form. These data suggest that some stem cell-derived tumors must commit to a specific lineage in order to grow.

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UR - http://www.scopus.com/inward/citedby.url?scp=48449107168&partnerID=8YFLogxK

U2 - 10.1016/j.ccr.2008.07.011

DO - 10.1016/j.ccr.2008.07.011

M3 - Short survey

C2 - 18691544

AN - SCOPUS:48449107168

SN - 1535-6108

VL - 14

SP - 105

EP - 107

JO - Cancer cell

JF - Cancer cell

IS - 2

ER -

Even Cancers Want Commitment: Lineage Identity and Medulloblastoma Formation

Abstract

ASJC Scopus subject areas

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